Associate Director, Supply Chain Technology Delivery

Overview Alnylam is seeking an experienced leader to serve as Associate Director, Supply Chain Technology Delivery to support the digital enablement of end-to-end clinical and commercial supply chain operations. This role will drive digital innovation, strengthen compliance, and enhance operational performance to help Alnylam scale with agility and deliver business outcomes. The position reports to the Sr. Director, CMC, Manufacturing and Supply Chain Technology within the Research & Early Development (ReDev) and Technical Operations & Quality (TOQ) Technology organization. As a recognized subject matter expert, this leader will act as a hands-on IT practitioner for the Supply Chain organization-enabling scalable, compliant, and efficient processes for planning and execution across Raw Material, Drug Substance, Drug Product and Finished Goods. They will partner closely with the SAP Center of Excellence (COE), IT software and service suppliers (e.g. Software-as-a-Service, system integrators), and internal IT teams-including Data/AI, Infrastructure services, PMO to design, deliver, and manage the lifecycle of supply chain technology solutions. Hybrid role based in Cambridge, MA, with 3 days/week onsite. Responsibilities · Define and execute the IT supply chain solutions roadmap aligned with business priorities and digital transformation goals · Oversee the implementation and continuous enhancement to core supply chain technologies – including SAP, clinical supply management solutions, logistics Software-as-a-Service (SaaS) solutions, and analytics to support supply chain operations · Drive implementation of digital capabilities for demand & supply planning, sales & operations planning, material management, master data management, inventory management, production planning, detail scheduling, address blinding and randomization needs for clinical studies, external warehousing, cold chain packaging-labeling and distribution, order-to-cash process including order management, fulfillment, billing and revenue recognition, creating visibility to temperature sensitive product shipments across 3PL network,, global trade (import-export) and compliance · Ensure seamless system integration (API/EDI) across SAP and third-party partners (E.g. Contract Manufacturing Organizations, Labs,3PLs), SaaS solutions, and in-house manufacturing systems (e.g. Manufacturing Execution System) to enhance visibility across inbound/outbound logistics and inventory movements · Partner with the IT Data/AI team and the Supply Chain organization to establish data governance, standardized master and reference data standards, and scalable data models on the enterprise data platform to enable analytics and AI/ML capabilities for supply chain operations · Collaborate with the Supply Chain organization and the IT Data/AI team to define Supply Chain analytics requirements and deliver AI and analytics solutions that drive data-informed decision-making. Own end-to-end accountability for the lifecycle of supply chain applications - from strategy and design through deployment, sustainment, upgrades, continuous improvement, and retirement. Partner with the business to define business case and articulate outcomes, manage total cost of ownership of supply chain digital solutions · Ensure all systems meet GxP, data integrity, and global regulatory requirements (e.g. FDA 21 CFR), maintaining audit readiness and supporting uninterrupted supply of medicines · Drive operational excellence by ensuring reliability, performance, compliance, and high-quality support of supply chain systems · Oversee end-to-end delivery of initiatives and build strong partnerships with business stakeholders, IT teams, vendors, and Procurement Qualifications Required · Bachelor’s degree in Information Technology, Supply Chain, Engineering, or related field · 10+ years of experience in Supply Chain or IT for Supply Chain roles in biopharmaceuticals or life sciences industry · Proven track record with SAP ERP supply chain. Experience with other supply chain technologies · Exceptional stakeholder management and influencing skills with operations leaders and supply chain user base. Change management and transformation leadership · Experience with data and systems integration, analytics, working with system integrators and managing IT suppliers · Experience in regulated environments (GxP, computer systems validation, FDA 21 CFR regulations) · Knowledge of full System Development Life Cycle (SDLC) - requirements, design, implementation, integration and testing, release and deployment, operations & maintenance, decommissioning · Demonstrated success building and leading cross-functional teams · Strategic mindset with a pragmatic approach - balancing long-term vision with reliable delivery of measurable business outcomes · 10% travel maybe required Preferred · Master’s degree or MBA · SAP Supply Chain Management or other Supply Chain (ASCM/APICS) certifications · Working knowledge of EDI, APIs, system integration and data transfers · Experience with Agile & Scrum methodologies, leveraging Jira (or similar tools) for tracking projects risks, issues, tasks and user stories, and project management best practices. · Familiarity with pharmaceutical supply chain requirements, including serialization and track-and-trace systems, Time Out of Refrigeration (TOR) · Familiarity with emerging AI, data and digital capabilities (data models, data lakehouse architectures, knowledge graphs, agentic AI) #LI-LN1 #LI- HYBRID U.S. Pay Range $172,200.00 - $233,000.00 The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity). Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together. Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: About Alnylam We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another. At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.