Director, Multiomic Sciences, Quantitative Biosciences

Job description

Job Description At our company, we are committed to becoming the premier, research-intensive biopharmaceutical company and are dedicated to providing leading innovations and solutions for today and the future. Our Researchers serve as the driving force behind our Innovations. We identify and target mechanisms or pathways involved in the disease process, and invent novel treatments/therapeutics to address unmet medical needs. This exceptionally COMPLEX task represents one of the most MULTIDISCIPLINARY endeavours in the field requiring expertise across disease biology, cellular systems, translational science, bioengineering, and data-driven research. As Director, Multiomic Sciences, you will build and lead one of the industry's most advanced molecular biomarker and multiomics group, integrating Immunoassays, Mass Spectrometry, Genomics, Flow Cytometry, Single-cell technologies, and AI-enabled analytics to transform how disease biology is understood, therapeutic targets are validated, and medicines are developed. Your team will generate actionable biological insights, enable biomarker-driven decisions, de-risk drug development programs, and influence critical portfolio decisions across discovery and clinical development. This role sits at the intersection of molecular biology, biomarker sciences, multiomic technologies, translational medicine, and data science, creating a unique opportunity to redefine how molecular biomarkers are discovered, validated, and deployed across the R&D pipeline. We aspire to establish a global benchmark for molecular biomarker and multiomic sciences by combining leading-edge analytical platforms, human biology, and computational approaches to accelerate the discovery and development of transformative medicines and vaccines. This role is based at our state-of-the-art research facility in Biopolis, Singapore , and offers a unique opportunity to influence our scientific strategy while building a high-performing team dedicated to advancing Multiomics Sciences for drug discovery and development. If you are passionate about leading multidisciplinary scientific teams, advancing molecular biomarkers and multiomics technologies, and applying innovative approaches to transform our understanding of disease biology, we invite you to join us in pioneering the future of translational research for the biopharmaceutical industry. WHAT YOU CAN EXPECT … You will build and lead one of the industry's most advanced molecular biomarker and multiomics team, integrating cutting-edge immunoassay, mass spectrometry, genomics, flow cytometry and data science capabilities to transform how medicines are discovered and developed. Opportunity to shape strategy and build world-class capabilities for impacting pipeline decisions A collaborative and supportive environment that fosters scientific excellence, innovation, continuous learning, leadership development, and a culture where diverse perspectives and ideas are encouraged to thrive. WHAT YOU WILL DO … Contribute as a member of the Singapore Quantitative Biosciences (QB) Leadership Team, partnering with the Site Lead and fellow leaders to shape and deliver site strategy and priorities, foster external and internal partnerships, and promote an innovative, and compliant research environment. Lead and develop multiple inter-related teams within the Multiomic Sciences group, fostering a high-performing culture of collaboration, accountability, continuous learning, and shared ownership. Build organizational capability through talent development and workforce planning, while maintaining accountability for the group's performance, resources, and operational outcomes. Develop and execute group objectives, business plans, and Multiomic Sciences strategies aligned with Singapore QB, , and divisional priorities. Lead budget, forecasting, workforce planning, and resource allocation to deliver scientific, operational, and financial objectives while ensuring compliance with company policies, quality and regulatory requirements, data integrity standards, and EHS practices. Influence senior scientific and business leaders to align investments, portfolio priorities, and resource allocation with organizational and business objectives. Provide scientific leadership to define and execute the Multiomic Sciences strategy, establish investment priorities, and build a differentiated portfolio of molecular biomarker and multiomic capabilities, including immunoassays, mass spectrometry, genomics, flow cytometry, and advanced omics technologies, to address current and future portfolio needs and strengthen long-term organizational capabilities. Drive innovation and scientific excellence through the evaluation, adoption, and advancement of emerging biomarker technologies, next-generation omics platforms, and AI/ML-enabled analytical approaches that enhance scientific insight, improve translational impact, and create new opportunities for therapeutic discovery and development. Lead the deployment and application of molecular biomarker and multiomic strategies to support target discovery and validation, mechanism-of-action studies, biomarker qualification, patient stratification, pharmacodynamic assessments, translational research, and data-driven decision-making across discovery and development programs. Partner with Therapeutic Area (TA) leaders and Singapore QB TA scientific leaders/point-of-contacts (PoCs) to leverage molecular biomarkers and multiomic approaches to inform critical go/no-go decisions, establish target engagement and proof-of-biology, support dose selection and patient stratification strategies, and accelerate the advancement of portfolio across discovery and clinical development. Build and influence strategic partnerships across internal functions, external research institutions, contract research organisations, healthcare systems, and technology providers to advance scientific priorities, accelerate execution, and enhance organisational impact. Represent the organisation as a scientific leader in molecular biomarkers and multiomics through publications, presentations, external collaborations, and scientific thought leadership. Influence scientific dialogue, shape industry perspectives, contribute to biomarker and multiomics strategy across therapeutic areas, and enhance the visibility, impact, and reputation of our science. WHAT YOU ARE EXPECTED TO HAVE … PhD in Molecular Biology, Biomedical Sciences, Life Sciences, Translational Medicine, Computational Biology, Bioinformatics, Systems Biology, Analytical Sciences, or a related discipline with at least 8 years of relevant industry experience, or a Master's degree in a related field with at least 12 years of relevant industry experience. Proven industry experience in drug discovery and development is required, and broad therapeutic area exposure across Oncology, Immunology, Neuroscience, and Cardiometabolic diseases strongly preferred. You should possess substantial scientific and leadership experience in molecular biomarker discovery, development, validation, and deployment to support drug discovery and development. Expertise may include one or more areas such as immunoassays, flow cytometry, mass spectrometry, genomics, transcriptomics, proteomics, metabolomics, single-cell technologies, biomarker sciences, translational medicine, computational biology, or related disciplines. Expertise in applying multidisciplinary molecular biomarker and multiomic approaches to elucidate complex biological mechanisms, validate therapeutic hypotheses, support biomarker strategies, and advance drug discovery and development is strongly preferred. Strong understanding of disease biology, mechanisms of action, biomarker qualification, translatability, clinical pharmacology, and translational medicine, with a proven ability to translate scientific insights into impactful R&D outcomes. Experience in building, leading, and developing high-performing multidisciplinary scientific teams, with experience in coaching, talent development, organizational change, capability building, workforce planning, and resource management will be considered as a strong plus. Effective at driving strategic outcomes, and fostering an inclusive, collaborative, innovative, and high-accountability culture. Demonstrate a strong strategic thinking ability, business acumen, and decision-making capabilities, with a demonstrated ability to navigate business complexity, solve challenging problems, assess risks and trade-offs, and make sound decisions that balance short-term execution with long-term organizational, portfolio, and capability goals. Demonstrated ability to anticipate scientific, technological, regulatory, and organizational trends and translate them into differentiated capabilities and portfolio impact. Strong leadership, influence, and communication skills, with a proven ability to build partnerships across functions and maximize the impact of people, capabilities, and investments. Demonstrated success aligning diverse stakeholders around strategic priorities, securing commitment to key initiatives, and ensuring the delivery of meaningful scientific and business outcomes. Finally, you are expected to have a strong capacity for change leadership and innovation, inspiring others to embrace new ways of thinking, working, and solving problems. Your ability to translate bold ideas into practical solutions that create measurable value will be critical to advancing organizational capabilities and delivering long-term impact. Who we are: We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world. What we look for: Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today. Required Skills: Assay Development, Assay Development, Biochemistry, Biomedical Sciences, Biopharmaceutical Industry, Biophysics, Business Acumen, Cell Biology, Computational Biology, Cytometry, Drug Discovery Research, Ethical Compliance, External Collaboration, Flow Cytometry, Functional Genomics, Immunology, Innovation, Life Science, Mentorship, Molecular Biology, Organizational Capability, People Leadership, Professional Networking, Proteomics, Strategic Thinking {+ 1 more} Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: VISA Sponsorship: Travel Requirements: Flexible Work Arrangements: Not Applicable Shift: Valid Driving License: Hazardous Material(s): Job Posting End Date: 10/1/2026 *A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.