Director, Pharmacometrics

Job description

Accountabilities: Lead and contribute to advanced pharmacometric modeling activities, including population PK, PK/PD, exposure-response, and model-based meta-analyses to support drug development decisions Apply quantitative methods such as disease modeling, trial simulation, dose optimization, and optimal study design to address complex clinical development questions Provide strategic input into drug development programs across multiple therapeutic areas, molecules, and stages of development Act as a scientific advisor to clients, supporting quantitative decision-making and enhancing development strategies through model-informed approaches Collaborate with cross-functional teams including scientists, consultants, and project stakeholders to deliver high-quality analytical outputs Conduct quality control and review of model code, datasets, and technical reports to ensure scientific rigor and compliance Contribute to internal methodological development, efficiency improvements, and innovation initiatives within the organization Potentially lead client engagements and support business development activities aligned with expertise and interests Requirements: PhD, MD, or PharmD in Pharmaceutical Sciences, Bioengineering, Pharmacology, Statistics, Applied Mathematics, Engineering, Medicine, or a related field 8–10 years of experience in pharmacometrics, clinical pharmacology, PK/PD modeling, or related quantitative disciplines Strong expertise in population PK, PK/PD, exposure-response modeling, and mechanistic or semi-mechanistic modeling approaches Proficiency in relevant tools and software such as NONMEM and R, along with strong statistical and programming capabilities Experience in clinical drug development, including trial design, execution, and regulatory support activities Proven ability to apply model-informed drug development approaches in both industry and consulting environments Strong analytical thinking, problem-solving skills, and ability to translate complex data into actionable insights Excellent communication and stakeholder management skills, with the ability to operate in multidisciplinary and client-facing settings Experience in consulting or cross-company project environments is highly desirable Benefits: Opportunity to work on high-impact global drug development programs across multiple therapeutic areas Strong exposure to advanced model-informed drug development methodologies and cutting-edge scientific approaches Collaborative, expert-driven environment with access to senior scientists and multidisciplinary teams Flexible working arrangements and international exposure Continuous learning opportunities and support for scientific and professional development Possibility to lead initiatives in methodology, innovation, and operational excellence Competitive compensation and comprehensive benefits package including healthcare and social protections How Jobgether works: We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team. We appreciate your interest and wish you the best! Why Apply Through Jobgether? Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time. #LI-CL1 This position is posted by Jobgether on behalf of a partner company. We are currently looking for a Director, Pharmacometrics in Switzerland. In this senior scientific leadership role, you will drive quantitative decision-making across drug development programs through advanced pharmacometric modeling and simulation. You will apply and oversee population PK, PK/PD, and exposure-response analyses to support strategic decisions across diverse therapeutic areas and modalities. Working at the intersection of science, data, and drug development strategy, you will collaborate with multidisciplinary teams and clients to shape development pathways and improve probability of success in clinical research. The role combines hands-on scientific expertise with consulting leadership, allowing you to influence both technical execution and high-level study design decisions. You will act as a trusted expert in model-informed drug development while contributing to methodological innovation and internal excellence initiatives. This position offers broad exposure to global pharmaceutical programs and a highly collaborative, science-driven environment.