Physician Scientist, Neuroscience & Ophthalmology Genetics

We are seeking a Physician Scientist to join our Neuroscience and Ophthalmology Therapeutic Area Genetics (TAG) team. We see this role as a subject matter authority in the translation of human genetic evidence into actionable insights in neurological, psychiatric, ophthalmological, hearing- and aging-related diseases. You will work closely with other teams in the Regeneron Genetics Center and Regeneron at large and be primarily responsible for designing, contributing to the execution of, and interpreting large and complex human genetic studies in the therapeutic areas. We hope you are excited by the opportunity to play a role in the development and implementation of innovative translational sciences and identify new therapeutic targets through genetic approaches. As a Physician Scientist in Neurology/Ophthalmology, a typical day might include the following: Applying human genetics to target discovery, selecting indications for drug programs, and identifying subgroups of patients who are more likely to respond to treatment through genetic analyses. Working with a multidisciplinary genetics team consisting of human genetics scientists, bioinformaticians, statistical geneticists, and other team members to design, execute, and interpret genetics studies in ophthalmology. Working in close collaboration with other Therapeutic Area Genetics team members and forming a strong partnership with Genome Informatics, Analytical Genomics, Clinical Informatics, and other RGC teams to deliver on complex, top-quality scientific endeavors in these Therapeutic Areas. Generating, summarizing, and presenting results in internal and external meetings to a variety of audiences. Leading or contributing to the writing of scientific reports and publications. Representing the TAG team in cross-functional initiatives within RGC and Regeneron. Collaborating with external industry and academic partners in scientific consortia. This job may be for you if: You have demonstrated the ability to design and lead human genetics studies delivering medically relevant findings in a team-based environment. You use medical knowledge to define relevant phenotypes for genetic association studies and to formulate innovative and important research questions. You have familiarity with clinical genetics concepts and various genetic models of disease. You have experience leading complex human genetics research endeavors, have knowledge of different study designs and analyses including GWAS, exome, or genome sequencing in cohort, case-control, or family-based studies, and have the ability to integrate different data resources to translate initial findings. You have an interest in understanding the genetic basis and causes of Neurological, Psychiatric, Ophthalmological, Hearing- and Aging-related diseases and translating this knowledge into therapeutic insights. An outstanding candidate will have previous experience with phenotypes related to these diseases. You thrive working in a highly interactive environment with a diverse team of colleagues. You have outstanding communication skills and an ability to summarize and present the results of human genetic studies to a variety of audiences. To be considered for this opportunity, you must have an MD or MD/Ph.D. with a strong background in and knowledge of human genetics or genetic epidemiology. An outstanding candidate will be an MD/Ph.D. with training and experience in translational human genetics, genetic epidemiology (or related disciplines), and strong quantitative skills. Familiarity with the applications of statistical genetics to gain medically actionable insights including polygenic risk scores, quantitative traits analyses, and Mendelian randomization, and familiarity with command-line interface, programming languages, and statistical software (eg. Python, R) is preferred. The outstanding candidate will have experience with the use of genetics in combination with other “omics” technologies (eg. epigenetics, proteomics, RNA-seq). Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter. Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location. As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications. For jobs in Canada: this posting is for an existing position. Salary Range (annually) $176,100.00 - $287,300.00