Physician Scientist, Therapeutic Area Genetics (Immunology)

We are looking for an extremely talented Scientist to join our Immunology Therapeutic Area Genetics (TAG) team. Within the RGC, the Immunology TAG team is using large-scale human exome sequencing for discovery and validation of new therapeutic targets in autoimmune and other immune-mediated disease. You will be responsible for designing and executing studies integrating large scale human genetics and multidimensional omics datasets derived from RGC and public resources in the immunology space to identify new targets for inflammatory and auto-immune diseases and accelerate target transition to novel therapeutics. You will collaborate with various RGC teams and with pre-clinical and clinical development teams at Regeneron to catalyze therapeutic development for genetically-validated targets in immunologic diseases. This role will require 4 days per week onsite at our campus in Tarrytown, NY. This is not available as a fully remote / hybrid work. In this role, a typical day might include the following: Understand and leverage RGC and Regeneron datasets, external resources, and the scientific/medical literature to generate research questions and then generate relevant phenotypes from longitiudinal clinical data, design and execute genetic association studies, and perform integrative omics analyses to address these research questions Deploy computational methods to integrate genetic data with multiple omics data to more effectively identify/prioritize drug targets illuminated by genetic association data. Work closely with other members of the Immunology and other TAG teams, Analytic Genetics, Sequencing, and GIDE in cross-functional initiatives within the RGC and Regeneron. Collaboratively summarize insights of investigations into a variety of formats (e.g. documents, presentations, patent applications, publications, etc.) for audiences with broad bacgrounds. Partner with Clinical Development to evaluate clinical stage programs and opportunities for human genetics studies to aid in the selection of indications or evaluation of safety considerations. This job might be for you if you can/have Bring innovative thinking to human genetics and epidemiological studies Experience leading complex human genetics research incorporating different analytic methods, phenotypes, and study designs. Ability to use medical knowledge to define relevant phenotypes for genetic association studies and to formulate innovative and important research questions. Worked with multidisciplinary teams to characterize the functional consequences of discovered disease gene variants Understanding of drug development and clinical trial design and execution. Experience in the clinical management or medical research relating to autoimmune and immune-mediated disease is a plus. To be considered for this opportunity, you must have a PhD , MD preferred with 8+ years of experience in the use of WES/GWAS datasets, RNA-Seq, proteomics and other large-scale platforms for genomic/proteomics. Demonstrated expertise in immunobiology, genetics, and mechanisms; familiarity with large genetic studies that deliver novel genetic findings and medically relevant gene discoveries; and demonstrated ability to manage and collaborate in a multi-disciplinary team, to discover and evolve immunology-related drug discovery pipelines. Individuals with proficiency in computational immunology research are particularly encouraged to apply. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter. Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location. As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications. For jobs in Canada: this posting is for an existing position. Salary Range (annually) $176,100.00 - $287,300.00