Post-Doctoral Fellow - Laboratory of Dr. Darren Moore

Van Andel Institute (VAI), a world-class biomedical research institute, located in Grand Rapids, Michigan, is dedicated to improving human health. We are pioneers in the fight against cancer, Parkinson's, and other diseases. We are committed to inspiring the next generation of scientists and educators. The Lab of Darren Moore in the Department of Neurodegenerative Science at Van Andel Institute is looking for a highly motivated Post-Doctoral Fellow to join a collaborative research program focused on the pathophysiological mechanisms underlying Parkinson’s disease. The position is available for an ambitious scientist to use or establish biochemical, cell biological and rodent models to investigate the pathogenic mechanisms underlying VPS35 or LRRK2 mutations in familial Parkinson’s disease. The laboratory employs a multidisciplinary approach in numerous experimental model systems, including primary neurons and astrocytes, human iPSC-derived models, rodents and human brain tissue, to elucidate the normal biological function and pathophysiological mechanisms of proteins linked to inherited forms of Parkinson’s disease, with a particular interest in the role and convergence of these proteins in the endolysosomal pathway. Qualifications A recent Ph.D. graduate with demonstrated experience in any of the following fields: cell biology, biochemistry and/or neuroscience. At least one publication in these fields would be desirable. A preferred candidate will have experience in any of the following research areas: primary culture-based assays; iPSC models; confocal imaging and quantitative analysis; development of genetic animal models; rodent neuropathology and behavior; or molecular/cellular neurobiology. Description of a Successful Candidate A self-motivated and driven individual who is able to exhibit exceptional research productivity and take responsibility for independent management of a project. A detail-oriented researcher who still keeps a clear grasp of the big picture. A team player who proactively shares knowledge and expertise with lab members. Excellent written and oral communication skills. How to Apply Qualified applicants should submit a single PDF including: Cover letter outlining research experience and fit with the lab Curriculum vitae Contact details for 2-3 references Applications will be reviewed on a rolling basis until the position is filled. For questions, please contact Natalie Hartford at or Darren Moore at . About Van Andel Institute Established in Grand Rapids, Michigan, in 1996 by the Van Andel family, VAI is now home to nearly 500 scientists, educators and support staff, who work with national and international collaborators to foster discovery. The Institute’s scientists study the origins of cancer, Parkinson’s and other diseases and translate their findings into breakthrough prevention and treatment strategies. Our educators develop inquiry-based approaches for K–12 education to help students and teachers prepare the next generation of problem-solvers, while our Graduate School offers a rigorous, research-intensive Ph.D. program in molecular and cellular biology. VAI is committed to excellence through broad participation and diverse perspectives. We welcome applications from individuals of all backgrounds and experiences who share our passion for innovation and collaboration. Van Andel Institute is an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. As Van Andel Institute is a drug free employer, all prospective new employees undergo a urinalysis/drug test as part of our pre-employment process. This is a 7-panel drug screen and it includes testing for Marijuana, Cocaine, Amphetamines, Opiates, PCP, Barbiturates, and Benzodiazepines. About Grand Rapids, MI Van Andel Institute is in downtown Grand Rapids, Michigan in the center of the Medical Mile . A remarkable combination of a cosmopolitan atmosphere and small-town warmth, Grand Rapids is known for its philanthropic and sustainability-driven community. It’s fun affordable and family-friendly. Located on the banks of the Grand River, Grand Rapids offers all the big-city excitement you'd expect from a million-resident metropolis, featuring hundreds of restaurants and nightspots, theaters, museums, sports and concerts. The safe and clean downtown is surrounded by an eclectic mix of walkable neighborhoods and natural areas. T he downtown area is safe and clean with an eclectic mix of walkable neighborhoods and natural areas.