Post Doctoral Scholar - Heart and Vascular Institute

Job description

APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process . Please do not apply here, apply internally through Workday. CURRENT PENN STATE STUDENT (not employed previously at the university) and seeking employment with Penn State, please login to Workday to complete the student application process. Please do not apply here, apply internally through Workday. If you are NOT a current employee or student, please click “Apply” and complete the application process for external applicants . Approval of remote and hybrid work is not guaranteed regardless of work location. For additional information on remote work at Penn State, see Notice to Out of State Applicants . This is a term position; length of the term will be discussed during the interview process. Continuation past the term length discussed will be based on university need, performance, and/or availability of funding. POSITION SPECIFICS The Penn State College of Medicine, Department of Heart and Vascular Institute, in Hershey, PA is seeking a Postdoctoral Scholar. This position in Dr. Shyam Bansal’s laboratory will study the role of inflammatory immune responses in mediating cardiovascular diseases. Our laboratory uses multidisciplinary approaches to study the role of different immune subsets in regulating left-ventricular remodeling and cardiac dysfunction during heart failure. Our research spans from human to animal studies, employing novel imaging and electrophysiologic techniques such as flow cytometry, vesicular analysis, and echocardiography. Duties include (but are not limited to): Perform small animal cardiac structure and functional analysis and conduct coronary ligation surgeries. This includes independently performing small animal echocardiography, real-time measurements of function using 2D, M-mode, & Doppler technology, as well as data analysis. Tissue harvesting, staining and flow analysis for immune cell subsets. Perform data analysis, and finally, write manuscripts/grants originating from this data. Isolate and perform analysis of exosomes Maintain cell line, perform pharmacological assays of cell lines with the microplate reader, perform Western blotting assays and quantitative RT-PCR assays. Independently monitor and carry out oversight of animal lines including transgenic mice colony maintenance, employing gel electrophoresis and PCR techniques. Analyze and plot data obtained from the assays performed. Provide training of other technicians to ensure that duties above are properly and aptly executed. The candidate will also be expected to analyze the data collected and present the results in formal presentations, manuscripts, and grant applications. Specific criteria include: Effective knowledge - Knowledge of lab practices and procedures in animal handling, dissection, Western blotting, PCR, fluorescence imaging, sub-cloning, and transfection. Accountability & Self-Management - Work independently, with minimal supervision by PI. Perform routine duties using established procedures with coordination and effective communication with the PI. Teamwork & Leadership - Independently develop and implement laboratory policies, update standard operating procedures that should ensure safe practices for all laboratory members. Communication - Communicate effectively with PI and other laboratory members as the projects are executed. Excellent verbal and written communication required for manuscript and grant preparation. Innovation & Problem Solving - Will contribute to the optimization of experimental procedures that require novel approaches. Education Requirements: The successful candidate will possess a doctoral degree with expertise in molecular biology, experience with in-vivo and in-vitro models of inflammation testing, and experience with flow cytometry. Experience with cell culture techniques and demonstrated ability to isolate and culture primary cells is essential. Highly motivated candidates should apply for the position online by uploading a cover letter describing your relevant experience, your current curriculum vitae, and the names of at least 3 job references. BACKGROUND CHECKS/CLEARANCES Employment with the University will require successful completion of background check(s) in accordance with University policies. BENEFITS Penn State provides a competitive benefits package for full-time employees designed to support both personal and professional well-being. For more detailed information, please visit our Benefits Page. 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