Principal Product Manager, Core AI
twinhealth
Remote, USA · Remote · USA
Posted Aug 21, 2026
- Other
- Remote
- Product
twinhealth
Remote, USA · Remote · USA
Posted Aug 21, 2026
Twin Health
At Twin Health, we empower people to improve and prevent chronic metabolic diseases, like type 2 diabetes and obesity, with a new standard of care. Twin Health is the only company applying AI Digital Twin technology exclusively toward metabolic health.
We start by building a dynamic model of each person’s metabolism — drawing on thousands of data points from CGMs, smartwatches, and meal logs — that maps their personal path to better health. Guided by a dedicated clinical care team, our members have lowered their A1C below the diabetes range, achieved lasting weight loss, and reduced or even eliminated medications, all while living healthier, happier lives.
Working here
Our team at Twin Health is passionate, talented, and united by a shared purpose: to improve the metabolic health and happiness of our members. We believe in empowering every Twin to make a meaningful impact for our members, our clients, and each other, while enjoying a supportive, collaborative work environment.
Twin has been recognized not only for our innovation but also for our culture, including: Innovator of the Year by the Employer Health Innovation Roundtable (EHIR), selected to CB Insights’ Digital Health 150, and named one of Newsweek’s Top Most Loved Workplace® .
With more than $100 million raised in recent funding, including a $53 million Series E round in 2025 led by Maj Invest, and a $50 million investment in 2023 led by Temasek, Twin is scaling rapidly across the U.S. and globally. Backed by leading venture firms like ICONIQ Growth, Sequoia, Sofina, Temasek, and Peak XV, we are building the most impactful digital health company in the world.
Join us as we reinvent the standard of care in metabolic health.
Opportunity
We are building a new interface to health: the Digital Twin.
The Digital Twin is a living, real-time model of each member’s metabolism and behavior—continuously learning from sensors, meals, sleep, movement, labs, and daily choices. It detects patterns, anticipates what’s coming, and guides members toward better health through timely, personalized actions.
To the member, it feels like a single, ever-present guide.
Under the hood, it’s a coordinated system of AI agents and human care working as one.
We’re looking for a Principal Product Manager to help define and build the core intelligence system at the heart of Twin.
This role sits at the intersection of:
You will:
Responsibilities
Qualifications
Compensation and Benefits
The compensation range for this position is $205,000 - $240,000 annually.
Twin has an ambitious vision to empower people to live healthier and happier lives, and to achieve this purpose, we need the very best people to enhance our cutting-edge technology and medical science, deliver the best possible care, and turn our passion into value for our members, partners and investors. We are committed to delivering an outstanding culture and experience for every Twin employee through a company based on the values of passion, talent, and trust. We offer comprehensive benefits and perks in line with these principles, as well as a high level of flexibility for every Twin
We have been made aware of fraudulent interview requests being sent using the Twin Health's name. All communications will come from official Twin Health channels and a twinhealth.com email address. We will never ask you to complete a text interview or request financial details during the interview process.