Principal Technology Portfolio Management Leader

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care. What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you. McKesson Technology (MT) has Enterprise Portfolio Management Office (EPMO) which is a centralized function to 1) enable consistent portfolio management 2) build and mature project and program management capabilities and 3) drive project management rigor and standards to enable value realization from investments. Principal Technology Portfolio Management Leader will be a key member of the EPMO team. The individual will be responsible for serving as a portfolio lead supporting Cybersecurity service area and a Business Unit. The individual in this role will need to be able to operate within a high level of ambiguity, remain calm under pressure and help establish structure and focus. Key Responsibilities : Drive the intake, prioritization, and sequencing of portfolio initiatives with cross-functional partners to ensure alignment with business strategy and maximize business outcomes. Monitor and track portfolio health by evaluating execution progress, interdependencies, risks, and capacity constraints, proactively recommending sequencing and highlighting issues to enable successful delivery and value realization. Drive connectivity and collaboration across delivery teams, Finance, and portfolio leads, influencing decisions that support achievement of business goals. Enable visibility into capacity constraints and facilitate alignment of priorities and trade-offs, ensuring resources are allocated to the most valuable initiatives. Establish and lead regular portfolio reviews with stakeholders and executive leadership, providing clear reporting on progress, financials, risks, lessons learned, and business impacts to inform decision-making. Drive annual budget planning with Finance, review baseline financials and investment budgets for initiatives, and collaborate with service managers to guide resource allocation and strategic decisions. Champion data-driven analysis and actionable insights, connecting project and technology spend to business value, and recommending trade-offs, course corrections, or project terminations as needed. Maintain portfolio governance and data integrity, ensure projects adhere to established frameworks, complete necessary lifecycle work, and have approved change requests for budget or schedule deviations. Build and maintain strong relationships with stakeholders, ensuring their needs and expectations are met through effective communication and delivery of portfolio information. Partner with Finance and embed benefits realization and value tracking into portfolio management by defining clear success metrics upfront, monitoring benefits during and after implementation, and reporting on KPI improvements, cost savings, and revenue growth. Promote transparency and alignment by providing stakeholders with visibility into how initiatives support strategic objectives, enabling informed prioritization and optimization of the portfolio’s cost/benefit mix. Support dynamic portfolio rebalancing, adapting to changes in business, financial, or capacity conditions to protect core operations while enabling innovation. Partner with Finance for ongoing financial forecasting, trend analysis, and investment mix reviews, ensuring high-value opportunities are funded and low-value projects are deprioritized. Anchor portfolio decisions in enterprise architecture, preventing proliferation of non-strategic platforms and ensuring alignment with target state architecture. Champion holistic performance and risk management, presenting portfolio health in business terms and elevating discussions from project status to business impact. Basic Skills and Experience : Degree or equivalent and typically requires 13+ years, with 8+ years of direct work-related experience. Less years required if has relevant Master's or Doctorate qualifications. Critical Skills and Experience : 8+ years of program and/or portfolio management experience with 5+ years of experience within a technology focused area (Cyber Security, Digital Transformation, IT Infrastructure, Cloud Modernization, etc.). Demonstrated experience collaborating regularly with VPs, SVPs, and C-suite executives, supported by a background in consulting. Exceptional executive presentation, communication, and influence management skills. Experience managing large portfolios and ensuring strategic alignment and prioritization, as well as overseeing investments and value realization—ideally within the technology sector, though a background in general technology combined with business portfolio management is also suitable. Experience delivering results by collaborating and influencing business and technology delivery teams in a highly matrixed organization. Proven stakeholder management skills & building credibility with executive leadership. Ability to intentionally flex between strategy and detail and adapt style to different levels of the organization. Experience driving organizational transformation and change management. Ability to make complex concepts simple and convey it laymen’s terms. Demonstrated ability to establish collaborative relationships and move with speed while bringing people along. High degree of emotional maturity and ability to remain calm and focused under pressure. Additional Knowledge & Skills desired but not required : Experience managing technology portfolio for a business unit or shared services function is highly desirable. Experience working in large matrixed organizations is highly desirable. Experience working with portfolio tools (Planview, Clarity PPM, etc.) is desirable. Experience in a highly regulated industry is desirable. Certification(s) in SAFe Agile, Prince2 / APM, PMP and/or Lean Six Sigma desirable. Travel : Hybrid role and may have to travel within the country up to 10% Relocation is not budgeted for this role We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here. Our Base Pay Range for this position $149,600 - $199,500 McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind: McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application. McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates. McKesson job postings are posted on our career site: . McKesson is an Equal Opportunity Employer McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page. McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) or (Canada) . Resumes or CVs submitted to this email box will not be accepted. Join us at McKesson!