Protein Purification Scientist

Job description

• Vaccine Immunotherapeutic (VITx) seeks to discover novel vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human disease using a variety of vaccine technology platforms combined with immunomodulatory agents. • A scientist is required to join Vaccine Immunotherapeutic in La Jolla, California, to develop and support vaccine platform production processes at the research scale • The candidate will have solid training and knowledge in mammalian cell culture and virus/protein purification • The candidate will be able to independently and proactively apply this knowledge in the design and execution of experimental work, to enable progression of vaccine discovery projects. • The candidate will be required to work semi-independently and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones • The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work. • Laboratory and related work (80-90% of time) under daily to weekly supervision. • Work with supervisor to define aim and a plan to achieve that aim, will then execute work following the plan (independently, if familiar with area of work, with guidance if unfamiliar) • Experimental design in consultation with supervisor, literature review, and increasing emphasis on independent design based on experience • Will carry out on-going analysis of data generated and will identify problems • Will implement necessary changes following discussion with peers/ supervisor. • Will analyze and interpret experimental data, results and methodology used with guidance. • Will gain skills and experience to be fully conversant with the operation and validation of all items of equipment or IT needed for experimentation, data analysis, storage and data entry. • Be able to review literature and suggest/apply to technical solutions to bioprocess problems of moderate complexity • Daily entry into electronic laboratory notebooks • Preparation of presentation materials. • Regular 1:1 communication with supervisor and team colleagues & Other colleagues within Vaccine Immunotherapeutic • Developing communication/presentation skills at internal meetings/poster sessions & Safe working and regulatory compliance. • Work safely themselves and be aware of EHS practices of other colleagues • Completion of risk assessments, compliance training as required • Acts independently to maintain a safe and EHS compliant desk and workspace • Experience in most or all of the following areas are essential- protein/virus purification using chromatographic techniques, experience with Unicorn based FPLC systems & tangential flow ultrafiltration and routine protein characterization techniques (SDS-PAGE, Western Blotting, BCA etc.) • In addition, experience in adherent and suspension mammalian cell culture along with transient protein expression is desirable. • The candidate will be required to work semi-independently and, as a member of a team, be accountable for the critical appraisal of their results and present them for review, at specific project milestones. The role is laboratory based, and a major emphasis is placed upon laboratory training to increase the scope of practical abilities, as well as the theory behind such practical work. • BSc or MSc in biological sciences or biochemical/chemical engineering • At least 1 year working in a laboratory in an academic or industrial settings Warm Regards Ricky Bansal 732-429-1925 A Few Words About Us Integrated Resources, Inc is a premier staffing firm recognized as one of the tri-states most well-respected professional specialty firms. IRI has built its reputation on excellent service and integrity since its inception in 1996. Our mission centers on delivering only the best quality talent, the first time and every time. We provide quality resources in four specialty areas: Information Technology (IT), Clinical Research, Rehabilitation Therapy and Nursing.