Regional Sales Business Director, South

praxisprecisionmedicines

United States - Remote · Remote · United States

Posted Aug 5, 2026

Other
Remote
Sales

Job description

Location: This is a remote-based role that requires flexibility and willingness to travel within a specified region and for company-related purposes as needed.

The Opportunity

Praxis Precision Medicines is entering a pivotal moment as we prepare for commercialization, and how we build and scale capability across the organization will directly impact our success. We are seeking a high-impact Regional Business Director to lead field execution and drive commercial performance across a defined geography. This leader will be responsible for managing and developing a team of field professionals while ensuring alignment with enterprise commercial strategy.

Working closely with cross-functional partners, you will play a critical role in delivering successful product launches, driving customer engagement, and building a high-performing regional organization.

What You’ll Do

Lead, coach, and develop a team of field sales professionals to achieve and exceed commercial objectives.
Drive execution of a unified commercial strategy across the region in alignment with enterprise priorities.
Partner with Commercial, Medical Affairs, Patient Services, and Market Access to deliver coordinated customer engagement.
Support field readiness and execution across pre-launch, launch, and post-launch phases.
Ensure teams are equipped with the capabilities, tools, and behaviors required for successful product launches.
Drive performance through clear goal setting, KPI tracking, and ongoing coaching.
Provide insights from the field to inform strategy and improve execution.
Build a strong, accountable, and high-performance team culture.
Ensure compliance with all regulatory and company policies.

What You Bring

5+ years of sales and/or strategic account management leadership within CNS or specialty pharmaceutical environments.
Demonstrated direct people management experience.
Recent national and regional awards recognizing top performance.
Evidence of consistent overachievement against commercial targets.
Proven CNS or specialty product launch experience, including participation in a full commercial launch cycle from pre-launch through post-launch execution.
Experience operating in agile, fast-moving organizations; biotech or emerging pharma preferred.
Ability to perform effectively in high-expectation, scaling environments.
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together!

To round out our world-class total rewards package, we provide annualized base salary in the range listed below. This range reflects the base salary the Company reasonably expects to pay for the position at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.

Annualized Base Salary

$220,000—$250,000 USD

Company Overview

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE^® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.