Research Associate II, Upstream Antibody Discovery

twistbioscience

USA - Quincy, MA · USA - Quincy · United States

Posted Jun 11, 2026

Other
Research & Development

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Job description

Research Associate II, Upstream Antibody Discovery

Job Description

We seek a Research Associate to support in vivo antibody discovery using our
high-throughput hybridoma process. In this lab-based role, attention to detail, strong
documentation and communication skills, and working independently and in group settings
will be critical for success. You will work directly with the Upstream Antibody Discovery team on
various projects to produce and scale hybridoma cell lines while supporting
the recombinant expression of antibodies and antigens.

What You’ll Be Doing
● Hybridoma generation, culture, scale-up, cryopreservation, and antibody production
● Mammalian cell culture
● Transient transfections in mammalian cells to support recombinant expression of
antibodies and antigens at a range of scales
● Media and buffer preparation
● Management of antibody discovery project timelines and deliverables
● Cross-functional coordination of workflows within the lab and with project managers
● Troubleshooting and continuous process improvement

What You’ll Bring to the Team
● Bachelor’s degree in a scientific discipline required
● Prior laboratory experience is strongly preferred, with priority toward experience in an
industry setting
● Mammalian cell culture experience with excellent aseptic technique
● Knowledge of antibody discovery processes a plus, with a preference toward
understanding hybridoma-based workflows
● Ability to troubleshoot scientific processes
● Excellent written and verbal communication skills
● Highly organized, detail-oriented, and able to operate in a fast-paced environment

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this Massachusetts-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

Massachusetts Pay Range

$75,000—$95,000 USD