Scientist III Protein Biology

Job description

Work Schedule Standard (Mon-Fri) Environmental Conditions Office Job Description About the company Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies & Services makes it easier for customers. About Team: Antibody team The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using pioneering tools and technologies. The goal of the program is advanced product development and creation of product specific information to promote research use. Role & Responsibilities Role: To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, and cell biology methods. Responsibilities: Perform in a fast-paced environment towards antibody development & testing Technical leadership in high throughput antibody development and testing platforms using integrated knowledge across protein biology, molecular biology and immuno-applications Informal leadership of team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists in research, design and experimental execution, interpreting data and data presentation to collaborators and partners. Drive conceptualization within teams to enable development of successful protocols for effective transfer to operation teams. Serve as authority in the field of immunoapplications and antibody development to provide inputs and guidance towards driving innovation and cross team collaborations. Partner with supporting functions such as product management, program management, operations, and business development to meet program goals. Candidate Requirement: Education & Experience levels: PhD with 5-7 years' experience, or Master’s degree with 10-13 years' experience Min 3-4 years of Industrial experience is required Nature of experience: Extensive experience and knowledge in immuno applications such as ELISA, Western Blotting, Immunofluorescence, Immunohistochemistry, flow cytometry etc. Familiarity or experience with next generation platforms such as spatial transcriptomics or proteomics will be a plus. Excellent understanding of antibody biology, structure and function. Experience and knowledge of different antibody development platforms such as phage display, single B cell technologies, hybridoma etc highly desirable. Good understanding and/or experience with protein purification and analysis technologies such as affinity or ion exchange chromatography, SEC, HPLC, and SDS-PAGE. Extensive experience and familiarity with antibody or protein engineering, rational design of mutants, and molecular biology. Experience with structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other such programs. Experience with antigen design for immunizations, analysis and identification of epitopic regions desirable. Familiarity or experience in development of conjugation chemistries or performing antibody conjugation. Project or work experience in support of relevant skills such as publications, project reports or thesis work. Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism. The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate to varied colleagues. Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. We offer attractive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. We offer employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer a company culture that stands for integrity, intensity, involvement, and innovation!