Ascendis Pharma is looking for a highly driven Associate Scientist (M.Sc.) or Scientist (Ph.D.) to join our Protein Chemistry team. In this role, you will play a key part in the design, synthesis, and characterization of therapeutic protein conjugates, supporting pre-clinical in vitro and in vivo studies.We are seeking a creative and collaborative scientist with a proactive mindset, strong problem-solving abilities, and a hands-on background in protein chemistry and bioconjugation. A positive, can-do attitude and a passion for innovation are essential.Are you energized by working in a team-oriented environment where mutual support, open communication, and knowledge sharing are part of the daily routine? Do you enjoy pushing the boundaries of science - exploring new ideas, technologies, and approaches - while maintaining a strong foundation of analytical rigor and critical thinking? Do you thrive on tackling complex scientific problems and excel in dynamic environments where priorities shift and goals evolve? Are you passionate about using your scientific expertise to contribute to the development of innovative therapies that make a real difference in patients’ lives?Your ResponsibilitiesDesign and optimize synthesis and purification workflows for protein conjugatesDevelop and implement advanced chromatographic and mass spectrometric techniquesConduct comprehensive characterization of protein conjugates, focusing on release profiles, stability, and biological activityExplore and assess innovative technologies to enhance our existing platform capabilitiesCommunicate findings effectively within cross-functional project teamsPrepare detailed scientific documentation, including technical reports and patent example draftsPerform in-depth literature reviews to support ongoing research and developmentRequirementsExceptional Master’s degree (Associate Scientist) or doctoral degree (Scientist) in biochemistry or a closely related fieldStrong theoretical foundation and hands-on expertise in protein chemistry and analytical techniques, including SEC, IEC, SDS-PAGE, RP-HPLC, bioconjugation, and TFFDemonstrated proficiency in operating Äkta and Agilent chromatography systemsSolid understanding of protein mass spectrometryProven creativity in developing synthetic strategies for complex protein conjugatesCollaborative mindset with a strong interest in interdisciplinary researchIndependent, well-organized, and methodical approach to workExcellent written and verbal communication skills in English; working proficiency in German is desirable BenefitsOnboarding:A structured Onboarding program designed to help you settle in quickly and get familiar with your role and our company cultureLearning & Development:Customized training opportunities with generous financial support to foster your professional growthConnectivity & Mobility:Direct access to the main station and to tram station, parking spaces for both cars and bicyclesWe offer a JobTicket based on the Deutschlandticket, and after your probation period, you’ll have the option to lease a JobRad (company bike)Food & More:Enjoy free soft drinks, fresh fruit, a wide variety of snacks, and a complimentary lunch every dayCompensation & Benefits:An attractive salary package including a company pension plan (bAV), internet allowance, and both short- and long-term incentive programsModern Work Environment:Your new workspace comprises working in brand new labs and comes equipped with a laptop and an iPhoneIf you want to be part of our team, we offer you an exciting and challenging full-time position with attractive benefits in an international company. Send your comprehensive application out now!
Ascendis Pharma is looking for a highly driven Associate Scientist (M.Sc.) or Scientist (Ph.D.) to join our Protein Chemistry team. In this role, you will play a key part in the design, synthesis, and characterization of therapeutic protein conjugates, supporting pre-clinical in vitro and in vivo studies.
We are seeking a creative and collaborative scientist with a proactive mindset, strong problem-solving abilities, and a hands-on background in protein chemistry and bioconjugation. A positive, can-do attitude and a passion for innovation are essential.
Are you energized by working in a team-oriented environment where mutual support, open communication, and knowledge sharing are part of the daily routine? Do you enjoy pushing the boundaries of science - exploring new ideas, technologies, and approaches - while maintaining a strong foundation of analytical rigor and critical thinking? Do you thrive on tackling complex scientific problems and excel in dynamic environments where priorities shift and goals evolve? Are you passionate about using your scientific expertise to contribute to the development of innovative therapies that make a real difference in patients’ lives?
Your Responsibilities
- Design and optimize synthesis and purification workflows for protein conjugates
- Develop and implement advanced chromatographic and mass spectrometric techniques
- Conduct comprehensive characterization of protein conjugates, focusing on release profiles, stability, and biological activity
- Explore and assess innovative technologies to enhance our existing platform capabilities
- Communicate findings effectively within cross-functional project teams
- Prepare detailed scientific documentation, including technical reports and patent example drafts
- Perform in-depth literature reviews to support ongoing research and development
Requirements
- Exceptional Master’s degree (Associate Scientist) or doctoral degree (Scientist) in biochemistry or a closely related field
- Strong theoretical foundation and hands-on expertise in protein chemistry and analytical techniques, including SEC, IEC, SDS-PAGE, RP-HPLC, bioconjugation, and TFF
- Demonstrated proficiency in operating Äkta and Agilent chromatography systems
- Solid understanding of protein mass spectrometry
- Proven creativity in developing synthetic strategies for complex protein conjugates
- Collaborative mindset with a strong interest in interdisciplinary research
- Independent, well-organized, and methodical approach to work
- Excellent written and verbal communication skills in English; working proficiency in German is desirable
Benefits
Onboarding:
A structured Onboarding program designed to help you settle in quickly and get familiar with your role and our company culture
Learning & Development:
Customized training opportunities with generous financial support to foster your professional growth
Connectivity & Mobility:
Direct access to the main station and to tram station, parking spaces for both cars and bicycles
We offer a JobTicket based on the Deutschlandticket, and after your probation period, you’ll have the option to lease a JobRad (company bike)
Food & More:
Enjoy free soft drinks, fresh fruit, a wide variety of snacks, and a complimentary lunch every day
Compensation & Benefits:
An attractive salary package including a company pension plan (bAV), internet allowance, and both short- and long-term incentive programs
Modern Work Environment:
Your new workspace comprises working in brand new labs and comes equipped with a laptop and an iPhone
If you want to be part of our team, we offer you an exciting and challenging full-time position with attractive benefits in an international company. Send your comprehensive application out now!
Founded in Copenhagen, Denmark in 2007, Ascendis Pharma is applying its innovative platform technology to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients’ lives. Guided by our core values of patients, science and passion, we utilize our innovative TransCon™ technology platform to create new and potentially best-in-class therapies.Today, we’re advancing programs in Endocrinology Rare Disease, Oncology, and Ophthalmology. We currently have five product candidates in clinical development: three in Endocrinology Rare Disease and two in Oncology. In addition, Ascendis recently announced new pre-clinical programs in Ophthalmology. We are a dynamic, growing biopharma company with headquarters in Copenhagen and additional offices and research facilities in Germany (Heidelberg, Munich, and Berlin) and the United States (Palo Alto, California, and Princeton, New Jersey).
Founded in Copenhagen, Denmark in 2007, Ascendis Pharma is applying its innovative platform technology to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients’ lives. Guided by our core values of patients, science and passion, we utilize our innovative TransCon™ technology platform to create new and potentially best-in-class therapies.
Today, we’re advancing programs in Endocrinology Rare Disease, Oncology, and Ophthalmology. We currently have five product candidates in clinical development: three in Endocrinology Rare Disease and two in Oncology. In addition, Ascendis recently announced new pre-clinical programs in Ophthalmology.
We are a dynamic, growing biopharma company with headquarters in Copenhagen and additional offices and research facilities in Germany (Heidelberg, Munich, and Berlin) and the United States (Palo Alto, California, and Princeton, New Jersey).
