Senior Director Clinical Development, Solid Tumor

Job description

Accountabilities: Lead clinical development strategy and create comprehensive clinical development plans that address worldwide regulatory, clinical, commercial, and patient-access considerations for assigned partnership programs. Provide senior clinical and scientific leadership across development programs, ensuring studies are appropriately planned, executed, and delivered within required quality, scope, and timelines. Partner closely with cross-functional program teams and execution units to support seamless implementation and high-quality delivery of clinical studies. Provide scientific expertise in the selection of investigators, vendors, CROs, and other external partners. Offer ongoing medical and scientific guidance throughout clinical trial conduct and serve as a senior escalation point for asset-related clinical issues. Review, analyze, interpret, and communicate clinical trial data for internal decision-making and external presentations. Build and maintain strong relationships with investigators and key opinion leaders and lead advisory boards, investigator meetings, and other scientific engagements. Author, review, and oversee key clinical development documents, including protocols, amendments, informed consent documents, Investigator Brochures, clinical study reports, abstracts, manuscripts, and clinical sections of regulatory submissions. Provide clinical input into INDs and equivalent applications, NDAs and equivalent submissions, annual reports, safety updates, health authority briefing materials, orphan drug applications, risk-benefit assessments, and clinical development plans. Respond to clinical and scientific questions from investigators, CROs, clinical monitors, regulatory authorities, and other stakeholders regarding study design, data analysis, and interpretation. Provide therapeutic-area training and guidance to execution teams, CRO personnel, and study sites, while coaching and mentoring clinical development colleagues. Conduct regular program reviews with execution teams and partnership stakeholders to assess study progress, operational KPIs, quality metrics, risks, and timelines. Contribute to therapeutic-area research, competitive intelligence, indication assessments, and broader clinical development strategy. Promote a global approach to clinical development, encouraging consistency, collaboration, continuous improvement, and effective knowledge sharing across teams. Manage and develop direct reports, including Medical Directors and Clinical Scientists supporting assigned programs. Participate in organizational standards, processes, and policy development and perform additional strategic responsibilities as required. Requirements: MD, DO, or equivalent medical degree in a relevant discipline. At least 6 years of clinical development experience, including 5 or more years focused on oncology; 10+ years of relevant experience is preferred. Deep professional knowledge of oncology therapeutics, with strong understanding of solid tumors and a deep understanding of immuno-oncology highly desirable. Demonstrated experience developing and executing clinical development strategies and plans across global programs. Strong understanding of international clinical development regulations, compliance requirements, and health authority expectations. Experience working effectively in a global, cross-functional environment with internal teams, CROs, investigators, regulatory agencies, and external partners. Proven ability to analyze and interpret clinical data and translate scientific findings into development strategy and business recommendations. Experience developing clinical and regulatory documentation, including protocols, clinical study reports, regulatory submissions, and related materials. Demonstrated ability to build productive relationships with investigators, key opinion leaders, advisory boards, and other external scientific stakeholders. Strategic leadership experience, including the ability to build, manage, mentor, and develop high-performing clinical development teams. Strong project management, prioritization, and decision-making capabilities, with the ability to manage multiple programs and competing priorities. Excellent written and verbal English communication skills, with the ability to present complex scientific information clearly to diverse audiences. Strong analytical thinking, data interpretation, collaboration, initiative, and results-oriented mindset. Ability to embrace change, operate with an entrepreneurial mindset, and navigate an evolving global development environment. Proficiency with Microsoft Office and standard business productivity tools. Willingness and ability to travel domestically and internationally, up to approximately 20%. Benefits: Base salary range of $299,800–$369,800 per year, with actual compensation determined by experience, skills, education, certifications, and work location. Eligibility for an annual bonus or incentive compensation program, depending on role classification and performance. Eligibility for discretionary equity awards and participation in an Employee Stock Purchase Plan. Comprehensive medical, dental, and vision coverage. 401(k) retirement plan. Flexible Spending Account (FSA) and Health Savings Account (HSA) options. Life insurance coverage. Paid time off. Wellness benefits and programs supporting employee well-being. Remote work opportunity within the United States. Opportunity to work on innovative oncology development programs within a global, cross-functional clinical development environment. Up to 20% domestic and international travel, providing opportunities for scientific and professional engagement. How Jobgether works: We use an AI-powered matching process to ensure your application is reviewed quickly, objectively, and fairly against the role's core requirements. Our system identifies the top-fitting candidates, and this shortlist is then shared directly with the hiring company. The final decision and next steps (interviews, assessments) are managed by their internal team. We appreciate your interest and wish you the best! Why Apply Through Jobgether? Data Privacy Notice: By submitting your application, you acknowledge that Jobgether will process your personal data to evaluate your candidacy and share relevant information with the hiring employer. This processing is based on legitimate interest and pre-contractual measures under applicable data protection laws (including GDPR). You may exercise your rights (access, rectification, erasure, objection) at any time. #LI-CL1 This position is listed on behalf of a partner company, who manages all applications and next steps. Our partner is looking for a Senior Director Clinical Development, Solid Tumor based in the United States. This is a senior clinical development leadership opportunity focused on advancing innovative oncology programs across solid tumor indications.You will own clinical development strategy and plans for partnership programs, ensuring they address global regulatory, clinical, and access requirements.The role combines scientific leadership, cross-functional collaboration, and hands-on oversight of clinical study execution from development planning through regulatory submission.You will work closely with internal execution teams, investigators, CROs, regulatory stakeholders, and external partners to deliver high-quality clinical programs.A major component of the position involves interpreting clinical data, shaping evidence-generation strategies, and translating insights into clear development decisions.You will also build relationships with key opinion leaders, mentor clinical development professionals, and contribute to a highly collaborative global oncology environment.This role is well suited to an experienced oncology physician leader who thrives in an agile setting and is motivated by accelerating meaningful therapies to patients worldwide.