Senior Director, Global Program Development Lead - DMD/Neuromuscular

Job description

**Who we are** REGENXBIO is an exceptional place to work. You'll have the opportunity to collaborate with some of the best and the brightest people, touch amazing science, and be a part of extraordinary plans. Our core values: Trust, Accountability, Perseverance, and Innovation drive everything we do. We aim to bring these values to life every day with all that we do, and we believe that what we do matters - to patients, to their families, and to their communities. **The opportunity** As a Senior Director, Global Program Development Lead (PDL), you will be in a highly visible leadership role that sits at the center of the cross-functional program team, to shape a compelling strategic direction, set ambitious priorities, and drive disciplined execution, in partnership with senior leadership. Leveraging deep expertise in drug development and commercialization, along with a forward-looking perspective and strong operational mindset, you will ensure the program team operates with clarity, rigor, and urgency while fostering collaboration and high performance. Accountable for cross-functional outputs, you'll guide the program’s path forward by anticipating opportunities, mitigating risks, cultivating strategic options, and driving decision-making amid complexity and uncertainty to achieve long-term program success. ### What you'll be doing - Lead overall program strategy, accountable for an integrated Program Development Strategy, Target Product Profile (TPP), and lifecycle management plan aligned with corporate objectives and long-term portfolio goals to maximize asset value. - Drive cross-functional strategic integration, ensuring scientific rigor and emerging clinical data, competitive intelligence, and evolving market dynamics inform program direction and critical decisions. - Identify key development challenges and define strategic options across functions, including timelines, budgets, risks, and trade-offs, enabling timely, high-quality decision-making. - Support business development activities, including opportunity assessment and due diligence; represent the program on Joint Steering Committees for partnered assets. - Maintain external perspective and scientific credibility through engagement with KOLs, patient advocacy groups, and other external experts. - Evolving and maturing the program’s external communications strategy in partnership with key groups, including the elements of scientific messaging, competitive positioning, and stakeholder alignment. - Drive cross-functional program execution within a matrix organization, ensuring high-quality, on-time deliverables while aligning priorities and resources to maximize program value and proactively resolve critical challenges. - Anticipate operational and strategic risks, establish contingency plans, and pressure-test assumptions, timelines, and budgets to maintain program agility and informed decision-making. - Serve as the primary liaison between the Core Team and governance committees, presenting program materials with clear, data-driven recommendations and actionable options to support timely approvals. - Build, influence, and sustain high-performing teams, guiding complex, high-stakes decisions without direct authority. - Lead cross-functional teams to deliver high-impact program outcomes, challenging assumptions, timelines, and budgets while developing alternative scenarios to mitigate risk and maximize value. - Own the quality, integrity, and timeliness of team outputs, ensuring company-level decisions are informed by robust, high-caliber data; set pace and priorities to achieve milestones in a highly competitive landscape. - Serve as the program spokesperson, aligning stakeholders and communicating strategy, progress, and decisions clearly across internal and external audiences. - Inspire innovation, scientific rigor, and creative problem-solving, fostering a culture of collaboration, continuous improvement, and boundary-less thinking. - Coach and develop team members to achieve peak performance, cultivating accountability, skill growth, and collective achievement. - Lead with pragmatism and clarity through ambiguity, charting the path forward and driving complex drug development decisions in fast-paced, dynamic environments. - Travel up to 20% - It is imperative that REGENXBIO employees embody our core values by working collaboratively, building strong relationships and using clear communication to meet shared objectives. ### What we're looking for - Bachelor’s degree required; advanced degree (MS, PhD, MBA) in life sciences or healthcare field preferred. - Proven leader with 8+ years in pharmaceutical industry leadership, with a strong track record driving drug development programs through pivotal stages to commercialization; product launch and early commercialization experience is a strong plus. - Strong understanding of drug development and commercialization processes, ideally within rare disease or gene therapy - Deep knowledge of neuromuscular diseases is highly desirable. - The ability to work well under intense pressure, tight timelines, and in rapidly changing situations - Evidence of an entrepreneurial spirit and a capacity to find creative solutions to unexpected hurdles - Interacts effectively across teams with supporting REGENXBIO functions and disciplines using influencing, communication and relationship building skills - Commitment to anticipate, influence and direct change - Excellent listening and collaboration skills