Senior Director, Marketing

olema

San Francisco, California · San Francisco · United States

Posted Apr 1, 2026

Other
Commercial

Job description

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. It’s an exciting time to be part of Team Olema, with our transformation into a fully integrated oncology company well underway, top-line data from our lead program expected later this year, and our first potential commercial launch on the horizon.

Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in the fall which, if successful, could lead to our first potential approval and commercial launch in 2027. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant has the potential to transform the metastatic breast cancer treatment paradigm and access a $15 billion global market opportunity.

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently reported encouraging Phase 1 monotherapy data from this program across multiple solid tumor types and are advancing patient enrollment in the ongoing combination arms in MBC.

Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and a passionate team dedicated to helping the patients we serve feel better, longer. We possess a deep commitment to our shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. Team Olema is made up of nimble self-starters who bring consistency in their quest for the extraordinary every single day.

If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond.

About the Role >>> Senior Director, Marketing

As the Senior Director, Marketing you will design and execute the Commercial roadmap that enables the successful potential U.S. launch of palazestrant, Olema’s lead program currently in Phase 3 for ER+ HER2- metastatic breast cancer. The ideal candidate will have experience in the commercialization of oral oncology therapies in breast cancer and a track record of leading successful oncology drug launches in the US.

This role is based out of our San Francisco office and will require travel as needed.

Your work will primarily encompass:

Building the strategic marketing plan and leading launch readiness initiatives (branding, positioning, messaging platform, story flow and creative imagery) to deliver a successful palazestrant launch
Developing, prioritizing, and implementing market development activities that deepen awareness of unmet needs and address knowledge gaps among customers
Designing the go-to-market approach that delivers resource-efficient customer engagement, customer behavior change and adoption at launch
Developing KPIs to assess launch performance and analyzing market, customer, and competitor trends, incorporating insights into marketing strategies and plans
Establishing a strong relationship with Medical Affairs, and eventually, the Sales team and other field-based commercial teams to ensure optimal execution
Partnering cross-functionally with Clinical Development, Regulatory and other internal stakeholders to gather input for functional activities and ensure alignment with launch readiness activities
Managing partner agency and vendor relationships and workflow
Ensuring strategic and tactical plans meet compliance and regulatory guidelines and company policies
Delivering marketing operating expenses within budget

Ideal Candidate Profile

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role.

Knowledge:

Bachelor’s degree required; MBA preferred
Deep understanding of customer adoption behavior in breast cancer
Knowledge of the laws and regulations regarding interactions with the healthcare community

Experience:

Minimum of 8 years of progressive commercial experience at biotechnology and/or pharmaceutical companies
Successful history of developing and executing marketing strategy plans and leading the launch of new oncology products in the US
Demonstrated ability to leverage insights and analytics to deliver impactful marketing strategies and tactics
Ability to influence effectively across an organization at all levels
Experience developing strategies to win in competitive markets
Experience thriving in a small company environment, with a hands-on and pragmatic leadership style
Excellent prioritization skills to deliver results within reasonably established timelines

Attributes:

Team player and collaborative: puts success of team above own interests; supports everyone's efforts to succeed; shares expertise with others
Possesses a get-the-job done attitude and identifies not just challenges but takes the initiative to identify solutions
Analytical thinking with problem-solving skills and the ability to adapt to changing priorities and deadlines
Excellent written verbal and interpersonal communication skills and ability to adapt communication styles to varied internal and external partners
Impeccable professional ethics, integrity, and judgment

The base pay range for this position is expected to be $250,000 - $285,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

#LI-AD1

Important Information >>>

We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants.

Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you.

Fraud Alert: We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview.