Senior Director, US Rare Disease Value and Access

Job title: Senior Director, US Rare Disease Value and Access Location: Cambridge, MA About the job Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. As Senior Director, US Rare Disease Value and Access within our US Rare Disease Leadership Team, you'll own payer-focused access strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You'll lead pricing, contracting, reimbursement, and GTN strategy to maximize formulary adoption and patient access. This role is a member of the US Leadership Team and reports directly to the General Manager. Ready to get started? You'll be joining Sanofi's US Rare Disease business at a pivotal moment—managing market access for a portfolio with clear growth trajectory to $3.1B by 2030, leading payer strategy for breakthrough therapies, and ensuring patients can access innovative treatments without delay. About Sanofi We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives. Main responsibilities: Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across rare disease portfolio Develop evidence-based market access strategies that maximize formulary adoption and patient access Create compelling value propositions for payers, providers, and key stakeholders Oversee and optimize GTN across the therapeutic area—pricing, rebates, and discounts by channel Monitor GTN performance and deliver recommendations to senior leadership to protect profitability Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales Lead GTN pull-through across all channels and geographies based on formulary position Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access Develop primary payer research and advisory board programs to close market access knowledge gaps Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions Define KPIs and track progress against access and financial targets Balance brand objectives and patient access priorities when they are in conflict Build, develop, and lead a high-performing team of 2 direct reports About you Role Overview: The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy — working backwards from what payers need to be convinced of value, often with limited trial data. In rare disease, access is not a downstream function: it is a strategic driver that shapes the commercial case from before launch. Beyond access expertise, the Head of Access Strategy must lead the function through the new era of AI-augmented evidence and value work. The six behaviors below apply to the whole leadership team; the ones this role leans on hardest are highlighted. Leadership Behavior : What It Means in the New Era 1. Leads with AI-augmented judgment Uses data and AI to decide faster and better — while owning the judgment calls AI cannot make. 2. Orchestrates across boundaries Delivers through influence, shared goals, and trust as functional silos dissolve — not through positional control. 3. Drives change and adoption Pulls the team through AI and digital change, creates psychological safety to experiment, and names resistance rather than tolerating it. 4. Obsesses over the patient outcome Anchors decisions to the patient's find-to-adherence journey, not functional activity metrics; treats advocacy and equity as strategic. 5. Models learning agility Reskills continuously, experiments, and fails fast in the open so the team does the same. 6. Builds talent density Runs lean with an elite bar: a few exceptional people, amplified by AI, outproduce larger teams. Makes the hard talent calls, raises the standard, and develops those they keep. Qualifications: Bachelor's degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred 10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms 7+ years of leadership experience managing teams and cross-functional initiatives Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management Proven track record in GTN management and financial modeling Strong financial acumen including P&L impact and pricing strategy Experience with value proposition development and payer evidence generation Experience in rare disease or specialty therapeutics preferred Excellent communication, negotiation, and executive influence skills Ability to navigate complex, highly regulated environments while managing multiple priorities Why choose us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave. Lead market access strategy for a high-growth $2.2B rare disease business with clear path to $3.1 Play a pivotal role in launching a landmark AATD therapy that will transform patient lives Join the US Leadership Team and shape payer strategy across the entire rare disease portfolio Drive formulary adoption and reimbursement for breakthrough therapies with cutting-edge HEOR, RWE, and payer evidence strategies Be part of a mission-driven team chasing the miracles of science to improve patients' lives. Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SG ​ #LI-GZ #LI-Onsite #vhd Pursue progress , discover extraordinary Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people. At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity. Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at ! US and Puerto Rico Residents Only Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. North America Applicants Only The salary range for this position is: $206,250.00 - $297,916.66 All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK .