Senior Machine Learning Engineer

onestudyteam

United States-Remote

Posted Dec 16, 2025

Full-time
Remote
Applied Machine Learning & Analytics

Job description

At OneStudyTeam (a Reify Health company), we specialize in speeding up clinical trials and increasing the chance of new therapies being approved with the ultimate goal of improving patient outcomes. Our cloud-based platform, StudyTeam, brings research site workflows online and enables sites, sponsors, and other key stakeholders to work together more effectively. StudyTeam is trusted by the largest global biopharmaceutical companies, used in over 6,000 research sites, and is available in over 100 countries. Join us in our mission to advance clinical research and improve patient care.

One mission. One team. That’s OneStudyTeam.

By joining our team as a Senior Machine Learning Engineer, you will play a pivotal role in building cutting-edge AI products that directly impact how new therapies reach patients. We’re looking for an experienced ML engineer who is passionate about turning advanced AI research into scalable, real-world solutions. You thrive on solving complex problems, pay close attention to detail, and consistently seek to automate and improve processes. You shine as a collaborator and excel as an individual contributor, with the courage to tackle challenging problems and the humility to learn and adapt. Your initiative and discipline allow you to thrive while working remotely, and your high degree of empathy and communication skills makes you the kind of colleague everyone wants on their team. As an integral member of our fast-growing organization, you will leverage AI to transform clinical research and improve patient care.

What You’ll Be Working On:

Build and deploy AI-driven products that accelerate clinical trials and improve patient outcomes. Your work will deliver scalable machine learning solutions to complex, real-world problems in clinical research.
Develop advanced ML models and LLM-powered agents for critical use cases like patient recruitment, enrollment forecasting, and study feasibility. You’ll also help expand our AI knowledge base architecture to support these innovative solutions.
Leverage modern cloud tools and MLOps best practices to build robust data pipelines and deploy models at scale. You’ll use technologies like Python (and Clojure), AWS services (Athena, Bedrock, SageMaker, etc.), dbt, Prefect, and CI/CD automation with monitoring to ensure models are reliable and up-to-date.
Collaborate across teams of data scientists, product managers, designers, engineers, and domain experts to integrate AI capabilities into our platform (including Care Access products). Ensure these AI solutions seamlessly support and enhance clinical research workflows for end-users.
Continuously learn and innovate. Stay up-to-date with the latest developments in ML/AI (LLMs, NLP, probabilistic modeling, etc.) and proactively bring new ideas to the team. You’ll have the freedom to experiment with cutting-edge techniques and turn promising prototypes into production features that drive our mission forward.

What You’ll Bring to OneStudyTeam:

Minimum Experience:
- Minimum of 5+ years of hands-on experience building and deploying machine learning solutions in production at scale. Proven ability to implement end-to-end ML pipelines from data ingestion to model serving for real-world applications used by real people.
Strong programming and data skills: Proficiency in Python and its ML ecosystem (pandas, scikit-learn, TensorFlow/PyTorch), with clean and efficient coding practices. Comfortable working with large datasets, writing complex SQL queries, and leveraging modern data processing frameworks. Experience with functional programming (e.g. Clojure) is a plus but not required.
Cloud and MLOps expertise: Experience with modern cloud infrastructure (AWS or similar) and containerization tools like Docker. Familiarity with MLOps best practices such as CI/CD pipelines, automated testing, and monitoring model performance/data drift to ensure reliable, scalable deployments.
Deep ML/AI knowledge: Strong understanding of machine learning fundamentals (model selection, training, evaluation, feature engineering) and statistical modeling. Familiarity with NLP and large language models is important.
Analytical problem-solving: Ability to break down complex problems and devise effective, efficient ML solutions. You balance pragmatic engineering with scientific rigor, ensuring models are not only accurate but also performant and maintainable in production.
Mission-driven and business-focused mindset: A passion for our mission to speed up clinical trials and improve patient outcomes. Empathy for patients, clinicians, and researchers drives you to build unbiased AI solutions.

The expected pay range for this role is $140,000 - $190,000 USD per year for full time team members.

#LI-Remote

We value diversity and believe the unique contributions each of us brings drives our success. We do not discriminate on the basis of race, sex, religion, color, national origin, gender identity, age, marital status, veteran status, or disability status.

Note: OneStudyTeam is unable to sponsor work visas at this time. If you are a non-U.S. resident applicant, please note that OneStudyTeam works with a Professional Employer Organization.

As a condition of employment, you will abide by all organizational security and privacy policies.

This organization participates in E-Verify (E-Verify's Right to Work guidance can be found here).

Mandatory Employer Disclosures:
Notice to Illinois applicants: Applicants are not obligated to disclose expunged juvenile records or adjudication, arrest, or conviction.
Notice to Connecticut applicants: OneStudyTeam may require applicants to submit to a urinalysis drug test in connection with an application for employment.
Notice to Arizona, Georgia, Indiana, and North Dakota applicants: OneStudyTeam complies with applicable laws prohibiting smoking in and around places of employment.
Notice to Massachusetts applicants: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Notice to Rhode Island applicants: OneStudyTeam complies with Rhode Island law prohibiting smoking in enclosed areas within places of employment. OneStudyTeam is also subject to is subject to Chapters 29–38 of Title 28 of the Rhode Island General Laws.
Notice to Maryland applicants: UNDER MARYLAND LAW, AN EMPLOYER MAY NOT REQUIRE OR DEMAND, AS A CONDITION OF EMPLOYMENT, PROSPECTIVE EMPLOYMENT, OR CONTINUED EMPLOYMENT, THAT AN INDIVIDUAL SUBMIT TO OR TAKE A LIE DETECTOR OR SIMILAR TEST. AN EMPLOYER WHO VIOLATES THIS LAW IS GUILTY OF A MISDEMEANOR AND SUBJECT TO A FINE NOT EXCEEDING $100.