Senior Scientist, R&D - Assay Development

Job description

Hims & Hers is the leading health and wellness platform, on a mission to help the world feel great through the power of better health. We are redefining healthcare by putting the customer first and delivering access to care that is affordable, accessible, and personal, from diagnosis to treatment to delivery. No two people are the same, so we provide access to personalized care designed for results. By normalizing health & wellness challenges and innovating on their solutions, we’re making better health outcomes easier to achieve. Hims & Hers is a public company, traded on the NYSE under the ticker symbol “HIMS.” To learn more about the brand and offerings, you can visit hims.com/about http://hims.com/about and hims.com/how-it-works http://hims.com/how-it-works . For information on the company’s outstanding benefits, culture, and its talent-first flexible/remote work approach, see below and visit www.hims.com/careers-professionals http://www.hims.com/careers-professionals. ABOUT THE ROLE: Hims & Hers is seeking a Senior Scientist, R&D to join our growing laboratory organization. This individual contributor will report to the Director of R&D and work closely to develop and validate diagnostic assays supporting both traditional and at-home testing programs, and support assay implementation into clinical operations. The ideal candidate is bench-strong, with hands-on experience across the full assay development lifecycle - from feasibility and optimization through verification and validation; and thrives in a fast-moving, early-stage environment This is an on-site laboratory role based in Central New Jersey. YOU WILL: Assay Development and Validation - Design and execute immunoassay development, optimization, and verification studies including ELISA, chemiluminescent, and multiplex formats - Perform method validation experiments including precision, accuracy, linearity, interference, and stability testing per established protocols - Apply Design of Experiments (DOE) and statistical methodologies to assay optimization and troubleshooting - Support LC-MS/MS method development and validation for clinical chemistry and hormone analytes - Evaluate performance characteristics of capillary versus venous specimens, investigate interference, and develop strategies to extend sample stability - Develop and revise SOPs to support consistent, reproducible laboratory operations - Prepare validation summaries, protocols, and technical reports in compliance with quality and regulatory standards Laboratory Execution - Perform hands-on laboratory testing using specimens collected via at-home devices such as Tasso and YourBio Health, including whole blood, plasma, serum, and other biological matrices - Operate LC-MS/MS instrumentation (SCIEX 4500MD or equivalent) including sample preparation, method validation, and data review - Support testing on automated chemistry and hematology platforms including Roche Cobas Pro and Sysmex systems, including CBC and whole blood analyte workflows - Support liquid handling automation workflows for sample processing and high-throughput laboratory operations - Troubleshoot assay performance issues across immunoassay, clinical chemistry, mass spectrometry, and molecular diagnostic platforms Data Analysis - Analyze experimental data and perform statistical evaluation of assay performance including precision, bias, and total allowable error modeling - Prepare figures, tables, and technical summaries for internal review and scientific communication - Contribute to peer-reviewed publications and scientific conference presentations Quality and Regulatory Collaboration - Partner with the Quality team to ensure study designs and documentation meet CAP, CLIA, and applicable regulatory requirements - Support investigation and resolution of sample rejection issues to improve overall laboratory quality metrics - Support laboratory inspection readiness and audit preparation activities - Collaborate with Clinical Laboratory Operations during assay transfer and implementation YOU HAVE: - PhD in Clinical Chemistry, Biochemistry, Analytical Chemistry, Molecular Biology, or related field with 4+ years; OR Master’s degree with 7+ years; OR Bachelor’s degree with 10+ years of relevant bench experience in a diagnostic or clinical laboratory setting - Demonstrated hands-on experience in immunoassay development including singleplex and multiplex formats - Experience with LC-MS/MS instrumentation including sample preparation and method validation - Experience with capillary and venous blood-based specimen types - Demonstrated experience leading assay validation and verification studies - Experience applying DOE and statistical methodologies to assay development and optimization - Proven ability to work independently and drive projects from concept to completion Preferred - Experience in a CAP and/or CLIA regulated laboratory environment - Experience with at-home or point-of-care diagnostic testing programs - Experience with dried blood spot (DBS) workflows and stability characterization - Familiarity with emerging biomarker categories relevant to metabolic health, longevity, and consumer wellness testing - Experience with NGS-based workflows including library preparation and bioinformatics data review OUR BENEFITS (THERE ARE MORE BUT HERE ARE SOME HIGHLIGHTS): - Competitive salary & equity compensation for full-time roles - Unlimited PTO, company holidays, and quarterly mental health days - Comprehensive health benefits including medical, dental & vision, and parental leave - Employee Stock Purchase Program (ESPP) - 401k benefits with employer matching contribution - Offsite team retreats We are committed to building a workforce that reflects diverse perspectives and prioritizes ethics, wellness, and a strong sense of belonging. If you're excited about this role, we encourage you to apply—even if you're not sure if your background or experience is a perfect match. Hims considers all qualified applicants for employment, including applicants with arrest or conviction records, in accordance with the San Francisco Fair Chance Ordinance, the Los Angeles County Fair Chance Ordinance, the California Fair Chance Act, and any similar state or local fair chance laws. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. Hims & Hers is committed to providing reasonable accommodations for qualified individuals with disabilities and disabled veterans in our job application procedures. If you need assistance or an accommodation due to a disability, please contact us at accommodations@forhims.com and describe the needed accommodation. Your privacy is important to us, and any information you share will only be used for the legitimate purpose of considering your request for accommodation. Hims & Hers gives consideration to all qualified applicants without regard to any protected status, including disability. Please do not send resumes to this email address. To learn more about how we collect, use, retain, and disclose Personal Information, please visit our Global Candidate Privacy Statement https://www.hims.com/global-candidate-privacy-statement.