Sr Manager, Oncology Business Assessments

ROLE SUMMARY Business Assessment (BA) is an exciting, highly collaborative, and dynamic team of professionals responsible for generating the investment cases for all pipeline and business development decisions. BA's assessments are independent by design: our credibility rests on applying the same rigor whether the analysis supports or challenges the case for investment. BA sits within Pfizer’s Global Commercial Analytics (GCA) organization under the Chief Marketing Office — a center of analytical excellence that unifies revenue forecasting across BD, in-line, and pipeline assets and elevates BA's strategic contribution across the full asset lifecycle. Our BA team is valued for proactive thought leadership, epi-forecasting expertise, innovative analytical capabilities, and ability to communicate complex and dynamic information in clear, concise, and creative ways. The BA Senior Manager owns discrete commercial assessments and forecasts end to end — building the model, framing the assumptions, and defending both — to inform investment decisions, partnering with colleagues across Research & Development, Global Commercial Strategy, the US and International commercial organizations, and Business Development (BD) to objectively evaluate internal pipeline and external opportunities against strategy and investment criteria. The Senior Manager works with a high degree of independence and is expected to be hands-on in the underlying models rather than directing others' analysis, ensuring thorough and consistent information to inform critical internal investment decisions and structure appropriate external deal terms. The Senior Manager will also provide strategic input into trade-off decisions that may be required between investment options, ensure consistency in assessment and forecasting approaches across external or internal investment options, and present analysis and recommendations directly to executive governance bodies. The role is anchored in Oncology, however, at times the senior manager may be asked to also cover disease area opportunities across multiple therapeutic areas (inflammation and immunology, internal medicine, vaccines), emerging technology platforms, and novel modalities — breadth of portfolio exposure that few commercial roles offer. ROLE RESPONSIBILITIES Build and own assessments of pipeline and BD opportunities — including epidemiology-based patient flow, treatment rates, uptake and persistency curves, gross-to-net price build — collaborating closely with cross-functional partners to ensure the analysis is rigorous, transparent, and based on common and well-supported modeling techniques and assumptions Take and defend an independent position — including recommending against an opportunity when the analysis does not support it, and doing so on incomplete information when the decision timeline requires it. This independence is the core of BA's value to Pfizer. Gather input from key internal expert stakeholders on the potential clinical development plan or clinical profile and commercial evaluation (e.g., Global Commercial Strategy, Integrated Insights & Strategy, Medical Affairs, Global Access Strategy & Pricing, Global Marketing/Regional leaders in the US and International Commercial Organization, Research and Development, Finance) Serve as commercial lead or co-lead of BD commercial subteams — owning the integrated workplan, framing the commercial narrative and 'what-must-be-true,' driving cross-functional alignment, and delivering decision-ready recommendations that inform deal structure and terms Integrate in-line and BD/pipeline forecasts - connect BD/pipeline assessments to in-line assumptions, cannibalization logic, and Long-Range Forecast (LRF) revenue projections AI-enabled assessment - use AI tooling as a standard part of the workflow: evidence and literature synthesis, competitive landscaping, model QC and error-checking, code-assisted analysis, and drafting of executive materials. Cycle-time gains are expected without any loss of rigor, and every assumption must remain traceable to its source. Scope and commission qualitative and quantitative primary market research with physicians, key opinion leaders, and patients, managing consulting and vendor resources while abiding by rigorous internal customer engagement protocols Develop analytically supported recommendations to facilitate investment trade off decisions across therapeutic area opportunities, as well as BD opportunities compared with internal pipeline investment Determine the appropriate level of rigor and external insights/research required, depending on the timeline and decision to be made Work flexibly and comfortably on multiple therapeutic areas in a matrixed team, as needed Support additional category and Pfizer portfolio-level projects (e.g., category strategy, knowledge management, best practice synchronization, professional development) or enterprise level initiatives and evaluations using internal forecasts, analyst reports, and other secondary data Basic Qualifications 6+ years (Bachelor’s degree) or 5+ years (Master’s degree) of relevant experience in the biopharmaceutical industry, life sciences consulting, or a comparable analytical function Advanced Excel proficiency — demonstrated ability to build, audit, and document multi-tab forecast models — plus strong PowerPoint skills for executive-level materials Demonstrated hands-on experience building or owning quantitative commercial forecast models, including patient-flow/epidemiology-based demand builds, uptake curves, gross-to-net pricing, and probability-of-success risk adjustment Experience using epidemiology literature, analyst reports, secondary/claims data, primary research, and pricing and market access inputs as the basis for a quantitative forecast Experience presenting analysis and recommendations directly to senior executive audiences, including engaging commercial and research leaders at the appropriate points in the assessment process Preferred Qualifications Prior experience in biopharma forecasting, life sciences consulting, financial services or other analytical professions MBA or life sciences advanced degree Experience in business development process, specifically in opportunity identification, commercial assessment, and deal structure Prior forecasting experience in Oncology Demonstrated use of AI/LLM tooling within an analytical workflow — evidence synthesis, model QC, code-assisted analysis — with assumptions kept traceable and auditable A track record of delivering an unfavorable or contrarian assessment that held up under senior scrutiny Proficiency in Python, R, or SQL for data handling, automation, and scenario analysis Experience influencing without direct authority in a matrixed organization, and supporting or leading cross-functional teams under compressed timelines with incomplete information Working knowledge of healthcare and pharmaceutical industry trends, competitor strategies, dynamics in the US and other major global markets, and the drug development process undefined Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Work Location Assignment: Hybrid Other Job Details: Last day to apply: September 22, 2026 The annual base salary for this position ranges from $124,400.00 to $207,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility. Candidates must be authorized to be employed in the U.S. by any employer. U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future. Sunshine Act Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States. Pfizer endeavors to make accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned. To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers . Marketing and Market Research