Sr Scientist, Analytical and Biological Mass Spectrometry (ABMS)

Build our future together: At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Sr. Scientist to join the Analytical and Biological Mass Spectrometry (ABMS) Group. In this role, you will work in an innovative liquid chromatography and mass spectrometry lab, developing and performing top-down and bottom-up mass spectrometry with state-of-the-art LC-MS instruments for therapeutic drug characterization. You will focus on the biochemical characterization of therapeutic proteins at all stages of drug development, developing and implementing LC/MS-based methods for protein primary structure elucidation — including peptide mapping, disulfide linkage determination, carbohydrate profiling, post-translational modifications, sequence variant analysis, charge and size variant characterization, and host-cell protein analysis. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide. When & where: Shift Requirements: Full-time Location: On-site in Tarrytown, NY Discover your role: Develop primarily LC/MS based analytical methods to support the development of monoclonal antibody-based therapeutic proteins, bispecific antibodies, Fc-fusion proteins, antibody conjugates, and other modalities (adeno-associated virus, mRNA, siRNA, etc.) Conduct analytical experiments and analyze LC-MS data to elucidate the quality attributes of therapeutic protein candidates, drug products, and critical reagents Develop LC-MS based bioanalytical strategies and high-throughput methods for quantitation of biomarkers and different types of drug candidates, including small molecules, peptides, oligonucleotides, monoclonal antibodies, antibody-drug conjugates, and other alternative novel modalities in biological matrices, to support preclinical and early-stage clinical PK studies Explore novel analytical and bioanalysis technologies and emerging platforms to meet the needs of an evolving portfolio that may include novel molecular modalities and new therapeutic areas Collaborate with therapeutic function areas to support drug discovery Bring strong organizational, communication, and interpersonal skills Learn new technologies quickly, with good problem-solving skills Bring enthusiasm for science and motivation to contribute in a team environment This role requires: Ph.D. in Analytical Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with 0-5 years of postdoctoral experience, or an MS degree with 5+ years of experience, or a BS degree with 7+ years of relevant experience Experience in liquid chromatography and mass spectrometry, with a proven track record of successfully developing MS, LC-MS, or LC-MS/MS methods Familiarity with sophisticated liquid chromatography and mass spectrometry technologies, and relevant software for data analysis Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter. Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location. As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications. For jobs in Canada: this posting is for an existing position. Salary Range (annually) $109,900.00 - $179,300.00