Translational Biomarker and CDx Leader -CDI - M/F

Job description

Who we are ? We are Pierre Fabre Laboratories, a global leader combining pharmaceutical expertise with dermo-cosmetics to support consumers and patients at every stage of their care journey. Our portfolio includes several medical franchises and international brands such as Eau Thermale Avène, Ducray, A-Derma, Klorane, René Furterer, and Pierre Fabre Oral Care. By joining us, you become part of a meaningful company where the human dimension is essential. You become a participant in the "We Care Movement," a movement that values excellence and innovation within passionate teams. Together, we push the boundaries of science to unite health and beauty for the benefit of all, because Every time we care for a single person, we make the whole world better. Present in 120 countries with a team of over 10,000 employees, we are proud to create a scientific and human impact, today and tomorrow! If caring is at the heart of your values, join Pierre Fabre Laboratories and become a key player in the “We Care Movement". Your mission We are seeking a talented and highly motivated Translational Biomarker and CDx Leader to join our growing Translational Research group within Pierre Fabre Pharma R&D. Pierre Fabre Pharma is committed to delivering novel, innovative therapeutic opportunities to patients in need, with oncology as a strategic priority. This is a unique opportunity to play a pivotal role in shaping precision oncology strategies at the intersection of cancer genomics, clinical biomarkers, companion diagnostics (CDx), and regulatory science. The successful candidate will lead clinical translational activities, with a primary focus on cancer genomics-driven biomarker and CDx strategies that enable rigorous testing of therapeutic and mechanistic hypotheses within clinical programs, from early- to late-stage clinical development. The position is based in Toulouse, France, with flexibility for commuting from France/Europe and home office. Your role within a pioneering company in full expansion: Responsibilities Develop and implement genomics-driven biomarker strategies to support patient selection and stratification in precision oncology programs. Oversee the application of NGS-based platforms and liquid biopsy technologies for biomarker discovery, MRD monitoring, and resistance profiling Lead CDx co-development in partnership with diagnostics companies, overseeing assay selection, analytical and clinical validation, bridging studies, and labeling strategies Engage cross-functionally with Clinical Development, Data Science, Biometry, PK/PD, and Regulatory teams to execute clinical biomarker plans and translational strategy, manage timelines, budgets, and risk mitigation across clinical studies Collaborate with clinical teams to develop comprehensive clinical documents such as study protocols and data management plans; manage internal and external resources, generate high-quality documentation for decision-making, and develop SOPs implementing best practices for genomic biomarker testing and CDx workflows Select and manage contract research organizations (CROs) and external testing vendors, ensuring quality clinical sample processing and timely biomarker data delivery. Proactively monitor the external pharmaceutical and clinical landscapes, to align internal directions with emerging industry advancements and best practices in precision oncology and cancer genomics. This position is compatible with teleworking up to 2 days a week according to company rules. We offer an attractive remuneration/benefits package: Incentives, profit-sharing, Pierre Fabre shareholding with matching contribution, health and provident insurance, 16 days of holidays (RTT) in addition to 25 days of personal holidays, public transport participation... Who you are ? Your skills at the service of innovative projects: PhD, MD/PhD or PharmD in cancer biology, human genetics, genomics, or molecular oncology. 7-12 years of experience in oncology translational research within pharma, biotech, or clinical CRO settings Proven track record of leading translational science activities and executing clinical-grade biomarker development strategies Prior regulatory experience with CDx co-development Hands-on experience with NGS-based platforms applied to oncology biomarker discovery and clinical translation. Proven expertise in liquid biopsy technologies (ctDNA, cfDNA) and their application in early detection, MRD monitoring, and resistance profiling Leadership Competencies Demonstrate effective leadership skills with experience in leading translational projects within a multi-functional matrix environment. Foster a collaborative and inclusive work environment through strong interpersonal and communication skills Employ a critical and objective approach to decision-making, grounded in science-based data and interpretation, with emphasis on applying these insights within clinical settings Define operational priorities and set ambitious, demanding objectives to drive success. Promote a culture focused on achieving results to maximize the quality of deliverables. Proactively monitor external pharmaceutical and clinical landscapes, encouraging the evolution of internal directions and approaches to align with industry advancements and best practices in precision medicine Excellent written and oral communication skills in English; knowledge of French is considered as a plus At Pierre Fabre Laboratories, we believe that our greatest asset is our people. We are committed to a policy of Equal Employment Opportunity and will not discriminate against an applicant or employee based on race, color, religion, creed, national origin or ancestry, sex, sexual orientation, gender identity or expression, age, physical or mental disability, veteran or military status, genetic information, or any other legally recognized protected basis under federal, state, or local law. The information collected by this application is solely to determine suitability for employment, verify identify, and maintain employment statistics on applicants. Applicants with disabilities may be entitled to reasonable accommodation under the Americans with Disabilities Act and certain state or local laws. Please inform the company’s personnel representative if you need assistance completing this application or to otherwise participate in the application process. Thus, we commit to considering all applications equally, without fail.